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[80] The damage to the bladder wall has similarities to both equally interstitial and eosinophilic cystitis. The wall is thickened as well as practical bladder capacity is as little as ten–a hundred and fifty mL.[79] Scientific studies reveal that ketamine-induced cystitis is brought on by ketamine and its metabolites instantly interacting with urothelium, causing problems in the epithelial cells with the bladder lining and elevated permeability with the urothelial barrier which ends up in medical symptoms.[eighty one]

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six)] The next adverse reactions connected to the use of ketamine hydrochloride have been identified in clinical research or postmarketing studies. Since A few of these reactions were being documented voluntarily from a inhabitants of uncertain sizing, It's not often feasible to reliably estimate their frequency or establish a causal marriage to drug exposure.

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